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Low Progesterone Protocol

by Paola Xhuli MSc MPH
Dec 07, 2025
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Progesterone is the dominant hormone of the luteal phase (the second half of your menstrual cycle). It is produced by the corpus luteum, a temporary gland formed from the ovulated follicle. Progesterone is essential for regulating cycles, supporting fertility and early pregnancy, balancing estrogen, improving sleep, calming the nervous system, and stabilizing blood sugar.

If you are not ovulating consistently or if the quality of the ovulated egg is poor, your corpus luteum will not produce enough progesterone. This is one of the most common hormonal imbalances in cycling women today.

Common Signs of Low Progesterone

  • Short luteal phase (less than 11 days)

  • Spotting before your period

  • PMS, mood swings, anxiety, or poor sleep

  • Fertility challenges or early miscarriage

  • Low body temperature in the luteal phase

  • Irregular or anovulatory cycles

  • Estrogen-dominant symptoms (heavy bleeding, breast tenderness, bloating)

Why It Happens (Root Causes)

Low progesterone is typically the result of a deeper imbalance rather than the problem itself. In cycling women, two main issues drive it:

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